PROTIEN SYNTHESIS
PROTEIN SYNTHESIS In 1958 Crick proposed that DNA determines the sequence of amino acid in a polypeptide through mRNA, this is the main principle or central dogma of protein synthesis which involves transcription and translation. Introduction – 1. Protein bio-synthesis is the process in which cells build or manufacture proteins . 2. The term is sometimes used to refer only to protein translation but more often it refers to a multi-step process, beginning with amino acid synthesis and transcription of nuclear DNA into m RNA , which is then used as input for translation. 3. The cistron DNA is transcribed into a variety of RNA intermediates. 4. The last version is used as a template in synthesis of a polypeptide chain. 5. Proteins can often be synthesized directly from genes by translating mRNA . When a protein must be available on short notice or in large quantities, a protein precursor is